I always find it really awkward when I'm emailing someone who has some kind of title and I keep calling them "Prof/Dr./Mr./Ms. So-and-so" when I address them and they keep signing off by their first name. Does that mean I should address them by their first name? If I am having a whole back-and-forth conversation via email, is there a point where I stop saying "Hello Prof/Dr./Mr./Ms. So-and-so," and just jump right into the response? Also is there a point where I just start signing off by my name instead of "Regards, My Name" or whatever? And if not, do I keep using the same "Regards" over and over, or do I have to switch it up with different phrases? Suggestions?